ABSTRACT
Chronic myeloid leukemia is a myeloproliferative disorder caused by a clonal disturbance of the trunk cell and the accumulation of granulocytic series in the marrow, blood and other organs. We report a 63 years old male, carrier of a chronic myeloid leukemia whose clinical condition was complicated by the appearance of a T cell lymphoma. He was subjected to chemotherapy, that reduced the size of adenopathies and improved his general condition. Further studies are required to determine if there is a relationship between these two clinical entities
Subject(s)
Humans , Male , Middle Aged , Lymphoma, Non-Hodgkin/complications , Leukemia, Myelogenous, Chronic, BCR-ABL Positive/complications , Splenomegaly/diagnosis , Splenomegaly/drug therapy , Lymphoma, Non-Hodgkin/diagnosis , Lymphoma, Non-Hodgkin/drug therapy , Busulfan/therapeutic use , Leukemia, Myelogenous, Chronic, BCR-ABL Positive/diagnosisABSTRACT
Se presenta una experiencia de tratamiento con clozapina en 11 pacientes esquizofrénicos resistentes. Se discute la eficacia del tratamiento y sus efectos adversos, así como la metodología empleada
Subject(s)
Humans , Adult , Schizophrenia/drug therapy , Clozapine/pharmacology , Prospective Studies , Treatment Outcome , Clozapine/administration & dosage , Clozapine/adverse effectsABSTRACT
We report a boy in whom an advanced Hodgkin's disease, nodular sclerosis variety was diagnosed at 5 yeras of age and treated with exclusive chemotherapy. After 16 years of remission, he presented with a relapsed of the disease with a different histological pattern and was subjected to chemotherapy (C-MOPP/AVB) and unilateral axillary irradiation, obtaining a complete remission of the disease. Four months later, the patients is asymptomatic and without evidences of relapse